Searchable abstracts of presentations at key conferences in endocrinology

ea0056oc2.2 | Look who is controlling your gonads! | ECE2018

Overexpressed kisspeptin/Kiss1R system in human granulosa cells may be involved in the pathogenesis of polycystic ovary syndrome (PCOS) by inhibiting ovulation

Hu Kai-Lun , Yu Yang

The kisspeptin/Kiss1R and neurokinin B (NKB)/ tachykinin receptor 3 (TACR3) system in the hypothalamus are essential for reproduction. Recent study suggested that the two peptide systems were both expressed in the ovary, particularly in the granulosa cells. To investigate the two systems in regulating the ovarian function, we collected the granulosa cells and follicular fluids from the 80 infertile patients (42 infertile control women and 38 PCOS women) undergoing IVF in Pekin...

ea0056p924 | Female Reproduction | ECE2018

Time-dependent regulation of kisspeptin/Kiss1R and TAC3/TACR3 systems expression in human ovarian granulosa cells from polycystic ovary syndrome (PCOS) patients and non-PCOS patients

Yu Yang , Hu Kai-Lun

The kisspeptin/Kiss1R and tachykinin 3 (TAC3)/tachykinin receptor 3 (TACR3) system in the hypothalamus are essential for reproduction. Recent study suggested that the two peptide systems are both expressed in the ovary, particularly in the granulosa cells. The expression profile of the two systems in human granulosa cells has not been fully investigated yet. We collected the granulosa cells from normal infertile control patients and patients diagnosed with PCOS in Peking Unive...